Psychiatry is rapidly adopting digital phenotyping and artificial intelligence/machine learning tools to study mental illness based on tracking participants’ locations, online activity, phone and text message usage, heart rate, sleep, physical activity, and more. Existing ethical frameworks for return of individual research results (IRRs) are inadequate to guide researchers for when, if, and how to return this unprecedented number of potentially sensitive results about each participant’s real-world behavior. To address this gap, we convened an interdisciplinary expert working group, supported by (...) a National Institute of Mental Health grant. Building on established guidelines and the emerging norm of returning results in participant-centered research, we present a novel framework specific to the ethical, legal, and social implications of returning IRRs in digital phenotyping research. Our framework offers researchers, clinicians, and Institutional Review Boards (IRBs) urgently needed guidance, and the principles developed here in the context of psychiatry will be readily adaptable to other therapeutic areas. (shrink)

As a member of the BRAIN Neuroethics Subgroup, which drafted the Neuroethics Roadmap, I am proud of our work. The Roadmap is the result of many hours of thoughtful discussion, and reflects strong l...

This book examines Fuller’s pioneering vision of social epistemology. It focuses specifically on his work post-2000, which is founded in the changing conception of humanity and project into a ‘post-‘ or ‘trans-‘ human future. Chapters treat especially Fuller’s provocative response to the changing boundary conditions of the knower due to anticipated changes in humanity coming from the nanosciences, neuroscience, synthetic biology and computer technology and end on an interview with Fuller himself. While Fuller’s turn in this direction has invited at (...) least as much criticism as his earlier work, to him the result is an extended sense of the knower, or ‘humanity 2.0’, which Fuller himself identifies with transhumanism. The authors assess Fuller’s work on the following issues: Science and Technology Studies (STS), the university and intellectual life, neo-liberal political economy, intelligent design, Cosmism, Gnosticism, agent-oriented epistemology, proactionary vs precautionary principles and Welfare State 2.0. (shrink)

Blaise Pascal began as a mathematical prodigy, developed into a physicist and inventor, and had become by the end of his life in 1662 a profound religious thinker. As a philosopher, he was most convinced by the long tradition of scepticism, and so refused – like Kierkegaard – to build a philosophical or theological system. Instead, he argued that the human heart required other forms of discourse to come to terms with the basic existential questions – our nature, purpose and (...) relationship with God. This introduction to the life and philosophical thought of Pascal is intended for the general reader. Strikingly illustrated, it traces the antithetical tensions in Pascal’s life from his infancy, when he was said to have been placed under the spell of a sorceress, to his final years of extreme asceticism. Pascal stressed both the misery and greatness of humanity, our finitude and our comprehension of the infinite. The book shows how his life, philosophical thought and literary style can best be understood in the light of the paradoxical view of human nature. It covers the methods of argument and the central issues of the Provincial Letters and of the Pensées ; the Introduction places Pascal’s thought in the religious and political climate of seventeenth-century France, and a ‘Chronology of the Life of Pascal’ is also included. (shrink)

The following reflections were originally an oral response to issues raised in Lee Yearley's presentation in May 2009 at Harvard Divinity School. As written here, they follow upon his oral and now written comments, highlighting key issues and points for development, drawing on this respondent's expertise in comparative and Hindu studies.

This essay explores a certain kind of uncertainty, a fuzziness, that occurs in inter-religious study where the religions involved both highly prize clarity, truth, and specific commitments. Reading that crosses religious borders creates a body of new insights and even spiritual experiences that neither fit easily into the settled doctrines of traditions nor contest those doctrines by offering new, liberal, or relativizing alternatives. Rather, productive spaces open up wherein spiritual insight and uncertainty go hand in hand, created and accentuated by (...) study, a stubborn fidelity to detail, and the ability to live with incertainty. By way of example, this essay offers an instance from a current study that the author, a Roman Catholic, is undertaking of intensely devotional medieval Hindu poetry, in part read along with passages from the biblical Song of Songs. The uncertainty carefully cultivated in this kind of study is, he argues, beneficial for those who remain committed to doctrinally robust traditions but also engage in the study of other, similarly robust traditions. (shrink)

This essay explores James Bernauer’s Jesuit Kaddish as an extended reflection on the centuries-long troubled relationship between Jesuits and Jews, with attention to egregious instances of moral fa...

The Ālvārs are the seventh–ninth century Tamil poet saints whose works achieved the status of sacred canon in what became, after the time of the theologian Rāmānuja, the Śrīvaiṣṇava community and tradition of south India. Their poems are honored as excellent poetry, as expressive of the experience of the poets themselves and of their encounters with Nārāyaṇa, their chosen deity, and finally as revelation, the divine Word uttered in human words. This thematic issue of Sophia is interested in investigating the (...) transformations or adaptations that a human language — speaking, writing — undergoes when transmitting a divine message, a revelation expressed in human words. This essay suggests that exploring how traditions have thought and performed the divine in human language can be undertaken usefully; that spiritual charged poetry is a powerful medium of divine communication in human words that both fall short in speaking of God and yet, in that failure, speak eloquently; and that reading intertextually, even interreligiously, is a way to disclose powerfully that divine communication. This essay reflects on all this by studying closely verse 57 of the Tiruviruttam of Śaṭakōpan, the greatest of these poet saints. It aims to show how even the outside reader — ‘the pilgrim reader’ who is neither a native nor a tourist — can enter into the interpretive process and find, in the elusive poetic words, a point of access to the revelation of the tradition. Some brief comparison is made with the interpretation of the Song of Songs in Jewish and Christian commentarial tradition. (shrink)

This essay introduces central features of classical Hindu reflection on the existence and nature of God by examining arguments presented in the Nyāyamañjarī of Jayanta Bhatta (9th century CE), and the Nyāyasiddhāñjana of Vedānta Deśika (14th century CE). Jayanta represents the Nyāya school of Hindu logic and philosophical theology, which argued that God’s existence could be known by a form of the cosmological argument. Vedānta Deśika represents the Vedånta theological tradition, which denied that God’s existencecould be known by reason, gave (...) primacy to the revelatory texts known as the Upanisads, and firmly subordinated theological reasoning to the acceptance of revelation. Jayanta and Deśika are respected representatives of their traditions whose clear, systematic positions illumine traditional Hindu understandings of “God” and the traditional Hindu debates about God’s existence and nature. Attention to their positions highlights striking common features shared by Hindu and Christian theologies, and offers a substantial basis for comparative reflection on the Christian understanding of God’s existence and nature, and the roles of reason and revelation in knowledge of God. (shrink)